Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.9
USERS' SCORE
Moderately Good
Based on 11 Reviews
7.6
Supplement Facts
Serving Size: 1 Vegetarian capsule
Amount Per Serving
%DV
Bio-Quercetin® Proprietary Blend providing 35% quercetin (10 mg) [from Japanese sophora concentrate flower bud)], 30% galactomannans (8 mg) [from fenugreek (seed)]
30 mg
**
Top Medical Research Studies
9.5
We explored the effects of quercitrin on platelet activation to better understand its role in blood clotting. Through comprehensive experiments—like assessing platelet aggregation and thrombus formation—we observed that quercitrin significantly hinders platelet activation. This means it impairs platelet aggregation and granule secretion, which are crucial in forming blood clots.
Moreover, quercitrin showed promise in preventing arterial thrombus formation without extending bleeding time, hinting at its potential as a treatment for thrombotic diseases. Overall, our findings suggest that quercitrin could be beneficial in managing blood clot-related conditions.
Moreover, quercitrin showed promise in preventing arterial thrombus formation without extending bleeding time, hinting at its potential as a treatment for thrombotic diseases. Overall, our findings suggest that quercitrin could be beneficial in managing blood clot-related conditions.
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8
We investigated how quercetin, a natural compound, can guard against the harmful effects of extracellular histones on platelets. Our study involved evaluating the interaction between histones and platelets in animal and lab settings.
We discovered that quercetin effectively inhibits histone-induced platelet activation and damage. This protection suggests that quercetin could be a valuable treatment option for conditions where histone toxicity plays a role, potentially assisting in the management of critical illnesses.
We discovered that quercetin effectively inhibits histone-induced platelet activation and damage. This protection suggests that quercetin could be a valuable treatment option for conditions where histone toxicity plays a role, potentially assisting in the management of critical illnesses.
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8
SXS shows promise against blood stasis
We investigated how Shi-Xiao-San, a traditional Chinese herbal formula, affects blood stasis, which relates to conditions like thrombosis and coronary heart disease. Through advanced techniques, we identified over 45 compounds, such as quercetin, that may play crucial roles in reducing blood viscosity and improving vascular health. Our tests showed that Shi-Xiao-San works by influencing key pathways involved in blood flow and inflammation. While promising, further studies are necessary to fully understand its mechanisms and benefits for treating blood clotting disorders.
Read More
Most Useful Reviews
9
Prevents clots
6 people found this helpful
I find this drug to be fantastic! Bio-Quercetin Life Extension is a bioflavonoid that enhances immune function. It helps maintain normal blood pressure and counteracts oxidative stress. Quercetin is particularly favoured for promoting healthy blood vessels by preventing blood clots and increasing capillary elasticity. It's a family-friendly supplement with proven results during treatment. I recommend it to everyone!
Read More
9
Significant improvements
1 people found this helpful
The quality is excellent. Bioavailable quercetin has significantly helped with issues related to blood vessels and capillaries. I used to have frequent bruises on my body, but after regularly taking this supplement, I've seen considerable improvements. Moreover, it acts as a good antioxidant, neutralising cancer cells. The capsules are small and easy to take. Its effectiveness is clear!
Read More
6
Strengthens capillaries
93 people found this helpful
We strengthen the capillaries with quercetin! This supplement not only fortifies the walls of larger blood vessels but also enhances the fine capillary network, which is crucial for preventing conditions that can lead to varicose veins and bruising. I’ve been incorporating rutin, quercetin, vitamin C, and bioflavonoids into my diet for a long time and find them beneficial against low blood pressure and weather sensitivity. A reputable nutritionist recommended this product to me, and I’m hopeful it will significantly contribute to my health.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.9
- All Researches
9.5
We explored the effects of quercitrin on platelet activation to better understand its role in blood clotting. Through comprehensive experiments—like assessing platelet aggregation and thrombus formation—we observed that quercitrin significantly hinders platelet activation. This means it impairs platelet aggregation and granule secretion, which are crucial in forming blood clots.
Moreover, quercitrin showed promise in preventing arterial thrombus formation without extending bleeding time, hinting at its potential as a treatment for thrombotic diseases. Overall, our findings suggest that quercitrin could be beneficial in managing blood clot-related conditions.
Moreover, quercitrin showed promise in preventing arterial thrombus formation without extending bleeding time, hinting at its potential as a treatment for thrombotic diseases. Overall, our findings suggest that quercitrin could be beneficial in managing blood clot-related conditions.
Read More
9
Quercetin as anticoagulant examined
We investigated the potential of quercetin, a compound from the African eggplant, to act as an anticoagulant. By using various methods including bioassay-guided fractionation, we studied its effects on blood clotting in mice. Our experiments revealed promising anticoagulant activities.
While quercetin shows effectiveness against clot formation, further research is needed to fully understand its mechanisms and therapeutic potential in treating cardiovascular diseases. Overall, this suggests quercetin may serve as a valuable herbal option for cardiovascular health.
While quercetin shows effectiveness against clot formation, further research is needed to fully understand its mechanisms and therapeutic potential in treating cardiovascular diseases. Overall, this suggests quercetin may serve as a valuable herbal option for cardiovascular health.
Read More
9
Taxifolin inhibits NETosis, aids thrombo-inflammation
We investigated how taxifolin, a bioactive flavonoid, could impact diseases associated with blood clots like lupus and antiphospholipid syndrome (APS). Using in vitro assays and mouse models, we observed that taxifolin significantly inhibits the formation of neutrophil extracellular traps—an action known as NETosis—linked to inflammation and clotting. Notably, taxifolin reduced autoantibody formation and large-vein thrombosis in these models. This pioneering study suggests that taxifolin may offer protective benefits against thrombo-inflammatory conditions, making it an exciting area for further research.
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9
We explored how Baiying Qingmai Formulation (BF) affects thromboangiitis obliterans (TAO) by analyzing its chemical makeup and how it interacts with various signaling pathways.
Our findings showed that BF significantly inhibits important proteins related to inflammation and blood clotting. It not only decreases harmful cytokines but also increases protective metabolites in the bloodstream.
Ultimately, we believe BF offers a promising path to alleviate symptoms of TAO by reducing blood clots and improving vascular health in affected individuals.
Our findings showed that BF significantly inhibits important proteins related to inflammation and blood clotting. It not only decreases harmful cytokines but also increases protective metabolites in the bloodstream.
Ultimately, we believe BF offers a promising path to alleviate symptoms of TAO by reducing blood clots and improving vascular health in affected individuals.
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We closely examined a retrospective study focused on how a blend of micronized flavonoids, including quercetin, can alleviate symptoms of grade II and III hemorrhoidal disease.
Patients taking this compound showed a notable 89.8% success rate in reducing hemorrhoid severity after just one week of treatment.
Improvements were seen across a range of symptoms with no reported side effects. Overall, this study suggests that quercetin, alongside other ingredients, may effectively help manage hemorrhoidal symptoms safely.
Patients taking this compound showed a notable 89.8% success rate in reducing hemorrhoid severity after just one week of treatment.
Improvements were seen across a range of symptoms with no reported side effects. Overall, this study suggests that quercetin, alongside other ingredients, may effectively help manage hemorrhoidal symptoms safely.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 11 Reviews
7.6
- All Reviews
- Positive Reviews
- Negative Reviews
9
Prevents clots
6 people found this helpful
I find this drug to be fantastic! Bio-Quercetin Life Extension is a bioflavonoid that enhances immune function. It helps maintain normal blood pressure and counteracts oxidative stress. Quercetin is particularly favoured for promoting healthy blood vessels by preventing blood clots and increasing capillary elasticity. It's a family-friendly supplement with proven results during treatment. I recommend it to everyone!
Read More
9
Significant improvements
1 people found this helpful
The quality is excellent. Bioavailable quercetin has significantly helped with issues related to blood vessels and capillaries. I used to have frequent bruises on my body, but after regularly taking this supplement, I've seen considerable improvements. Moreover, it acts as a good antioxidant, neutralising cancer cells. The capsules are small and easy to take. Its effectiveness is clear!
Read More
6
Strengthens capillaries
93 people found this helpful
We strengthen the capillaries with quercetin! This supplement not only fortifies the walls of larger blood vessels but also enhances the fine capillary network, which is crucial for preventing conditions that can lead to varicose veins and bruising. I’ve been incorporating rutin, quercetin, vitamin C, and bioflavonoids into my diet for a long time and find them beneficial against low blood pressure and weather sensitivity. A reputable nutritionist recommended this product to me, and I’m hopeful it will significantly contribute to my health.
Read More
7.5
Supports vein health
46 people found this helpful
This supplement is incredible! A dietary product from a trusted brand that I adore. It aids significantly with issues related to veins and blood vessels. Quercetin, a natural bioflavonoid, has been extensively studied for its numerous benefits, including protecting the brain and heart from oxidative stress and enhancing wound healing. It also possesses anti-inflammatory and immunomodulatory properties, making it ideal for improving cardiovascular health. I wholeheartedly recommend it to everyone!
Read More
7.5
Mild illness recovery
9 people found this helpful
An exceptional tool! After contracting COVID-19, I learned about quercetin's benefits in post-COVID treatment. I began taking it cautiously to combat blood vessel issues and inflammation while enduring the illness mildly. After recovery, my doctor praised my supplement choices, including quercetin. I plan to keep it handy for possible future viral infections. If you find this review helpful, please like it!
Read More
Frequently Asked Questions
9
Significant improvements
1 people found this helpful
The quality is excellent. Bioavailable quercetin has significantly helped with issues related to blood vessels and capillaries. I used to have frequent bruises on my body, but after regularly taking this supplement, I've seen considerable improvements. Moreover, it acts as a good antioxidant, neutralising cancer cells. The capsules are small and easy to take. Its effectiveness is clear!
7.5
Mild illness recovery
9 people found this helpful
An exceptional tool! After contracting COVID-19, I learned about quercetin's benefits in post-COVID treatment. I began taking it cautiously to combat blood vessel issues and inflammation while enduring the illness mildly. After recovery, my doctor praised my supplement choices, including quercetin. I plan to keep it handy for possible future viral infections. If you find this review helpful, please like it!
7.5
Strengthened blood vessels
My parents struggled with weak blood vessels, which led to frequent nosebleeds. This seems to have helped strengthen their blood vessels, reducing nosebleeds when taken with vitamin C.
5
Noticed minimal effectiveness
Quercetin is a good antioxidant and the brand quality is sound. It's small-sized, beneficial for blood vessels and immunity, though I haven't noticed a significant effectiveness myself.
6
Strengthens capillaries
93 people found this helpful
We strengthen the capillaries with quercetin! This supplement not only fortifies the walls of larger blood vessels but also enhances the fine capillary network, which is crucial for preventing conditions that can lead to varicose veins and bruising. I’ve been incorporating rutin, quercetin, vitamin C, and bioflavonoids into my diet for a long time and find them beneficial against low blood pressure and weather sensitivity. A reputable nutritionist recommended this product to me, and I’m hopeful it will significantly contribute to my health.
7.5
Supports vein health
46 people found this helpful
This supplement is incredible! A dietary product from a trusted brand that I adore. It aids significantly with issues related to veins and blood vessels. Quercetin, a natural bioflavonoid, has been extensively studied for its numerous benefits, including protecting the brain and heart from oxidative stress and enhancing wound healing. It also possesses anti-inflammatory and immunomodulatory properties, making it ideal for improving cardiovascular health. I wholeheartedly recommend it to everyone!
7.5
Good for corona
1 people found this helpful
A good drug that helps with blood vessels. It works especially well for corona, particularly when combined with vitamin D, zinc, and curcumin.
9
Prevents clots
6 people found this helpful
I find this drug to be fantastic! Bio-Quercetin Life Extension is a bioflavonoid that enhances immune function. It helps maintain normal blood pressure and counteracts oxidative stress. Quercetin is particularly favoured for promoting healthy blood vessels by preventing blood clots and increasing capillary elasticity. It's a family-friendly supplement with proven results during treatment. I recommend it to everyone!
6
Essential for covid
1 people found this helpful
A good drug that is essential to have for covid. It helps in thinning the blood effectively.
8
We investigated whether quercetin, along with other flavonoids, impacts platelet activity, which is crucial for blood clotting. Using blood samples from healthy volunteers, we looked at how these compounds influence the activation states of platelets through a specialized laboratory technique.
Our findings showed that quercetin and the other flavonoids demonstrated significant antiplatelet activity, effectively blocking a key receptor involved in platelet aggregation. This work helps shed light on how these natural compounds may play a role in preventing cardiovascular issues by reducing unwanted blood clot formation.
Our findings showed that quercetin and the other flavonoids demonstrated significant antiplatelet activity, effectively blocking a key receptor involved in platelet aggregation. This work helps shed light on how these natural compounds may play a role in preventing cardiovascular issues by reducing unwanted blood clot formation.
9
Quercetin as anticoagulant examined
We investigated the potential of quercetin, a compound from the African eggplant, to act as an anticoagulant. By using various methods including bioassay-guided fractionation, we studied its effects on blood clotting in mice. Our experiments revealed promising anticoagulant activities.
While quercetin shows effectiveness against clot formation, further research is needed to fully understand its mechanisms and therapeutic potential in treating cardiovascular diseases. Overall, this suggests quercetin may serve as a valuable herbal option for cardiovascular health.
While quercetin shows effectiveness against clot formation, further research is needed to fully understand its mechanisms and therapeutic potential in treating cardiovascular diseases. Overall, this suggests quercetin may serve as a valuable herbal option for cardiovascular health.
8
We investigated the potential of Traditional Chinese Medicine (TCM) for finding natural medications to combat blood clots. Focusing on the plant Ledeb, we screened its components for their ability to inhibit thrombin, a key player in clot formation. Using advanced techniques, we identified eleven compounds, including quercetin, that demonstrated antithrombotic properties. Our results showed that specific components could effectively reduce thrombin activity, offering promising insights into natural treatments for thrombotic diseases. However, further studies are needed to confirm these findings and understand the mechanisms involved.
7
We explored how quercetin-3-rutinoside, a type of bioflavonoid, affects blood clotting by inhibiting protein disulfide isomerase (PDI). Our study revealed that this compound effectively blocks PDI activity in various models of thrombus formation.
Through a combination of techniques such as NMR spectroscopy and biological assays, we pinpointed a specific residue crucial for this interaction. However, understanding the detailed mechanism behind this inhibition is still a work in progress.
While quercetin-3-rutinoside shows promise in clot prevention, much rigorous testing is needed before it can be considered a definitive treatment.
Through a combination of techniques such as NMR spectroscopy and biological assays, we pinpointed a specific residue crucial for this interaction. However, understanding the detailed mechanism behind this inhibition is still a work in progress.
While quercetin-3-rutinoside shows promise in clot prevention, much rigorous testing is needed before it can be considered a definitive treatment.
References
- Dai J, He W, Liu SA, Huang S, He X, et al. Rapid screening of the antithrombotic active components of Ledeb with thrombin binding affinity ultrafiltration mass spectroscopy. Anal Methods. 2025;17:2046. doi:10.1039/d4ay01909a
- Manikanta K, NaveenKumar SK, Hemshekhar M, Thushara RM, Mugesh G, et al. Quercetin inhibits platelet activation and ER-stress mediated autophagy in response to extracellular histone. Phytomedicine. 2025;138:156386. doi:10.1016/j.phymed.2025.156386
- Gauer JS, Ajanel A, Kaselampao LM, Candir I, MacCannell ADV, et al. Plant-derived compounds normalize platelet bioenergetics and function in hyperglycemia. Res Pract Thromb Haemost. 2024;8:102548. doi:10.1016/j.rpth.2024.102548
- Gogoi D, Chattopadhyay P, Dolui SK, Khan MR, Mukherjee AK. Studies on in vivo antithrombotic activity of quercetin, a natural flavonoid isolated from a traditional medicinal plant, African eggplant (Solanum indicum). J Ethnopharmacol. 2024;335:118686. doi:10.1016/j.jep.2024.118686
- Rysenga CE, May-Zhang L, Zahavi M, Knight JS, Ali RA. Taxifolin inhibits NETosis through activation of Nrf2 and provides protective effects in models of lupus and antiphospholipid syndrome. Rheumatology (Oxford). 2024;63:2006. doi:10.1093/rheumatology/kead547
- Fan W, Lan S, Yang Y, Liang J. Network pharmacology prediction and molecular docking-based strategy to discover the potential pharmacological mechanism of Huang-Qi-Gui-Zhi-Wu-Wu decoction against deep vein thrombosis. J Orthop Surg Res. 2023;18:475. doi:10.1186/s13018-023-03948-6
- Zou C, Liu L, Huang C, Hu S. Baiying qingmai formulation ameliorates thromboangiitis obliterans by inhibiting HMGB1/RAGE/NF-κB signaling pathways. Front Pharmacol. 2022;13:1018438. doi:10.3389/fphar.2022.1018438
- Wei X, Gao M, Sheng N, Yao W, Bao B, et al. Mechanism investigation of Shi-Xiao-San in treating blood stasis syndrome based on network pharmacology, molecular docking and in vitro/vivo pharmacological validation. J Ethnopharmacol. 2023;301:115746. doi:10.1016/j.jep.2022.115746
- Hu M, Peng X, Shi S, Wan C, Cheng C, et al. Sulfonated, oxidized pectin-based double crosslinked bioprosthetic valve leaflets for synergistically enhancing hemocompatibility and cytocompatibility and reducing calcification. J Mater Chem B. 2022;10:8218. doi:10.1039/d2tb01704k
- Liao X, Zhuang X, Liang C, Li J, Flaumenhaft R, et al. Flavonoids as Protein Disulfide Isomerase Inhibitors: Key Molecular and Structural Features for the Interaction. J Agric Food Chem. 2022;70:4475. doi:10.1021/acs.jafc.1c07994
- Gravina AG, Pellegrino R, Facchiano A, Palladino G, Loguercio C, et al. Evaluation of the Efficacy and Safety of a Compound of Micronized Flavonoids in Combination With Vitamin C and Extracts of , , and for the Reduction of Hemorrhoidal Symptoms in Patients With Grade II and III Hemorrhoidal Disease: A Retrospective Real-Life Study. Front Pharmacol. 2021;12:773320. doi:10.3389/fphar.2021.773320
- Manjunath SH, Thimmulappa RK. Antiviral, immunomodulatory, and anticoagulant effects of quercetin and its derivatives: Potential role in prevention and management of COVID-19. J Pharm Anal. 2022;12:29. doi:10.1016/j.jpha.2021.09.009
- Lee S, Yu Y, Trimpert J, Benthani F, Mairhofer M, et al. Virus-induced senescence is a driver and therapeutic target in COVID-19. Nature. 2021;599:283. doi:10.1038/s41586-021-03995-1
- Zaragozá C, Monserrat J, Mantecón C, Villaescusa L, Álvarez-Mon MÁ, et al. Binding and antiplatelet activity of quercetin, rutin, diosmetin, and diosmin flavonoids. Biomed Pharmacother. 2021;141:111867. doi:10.1016/j.biopha.2021.111867
- Rojas-Garbanzo C, Rodríguez L, Pérez AM, Mayorga-Gross AL, Vásquez-Chaves V, et al. Anti-platelet activity and chemical characterization by UPLC-DAD-ESI-QTOF-MS of the main polyphenols in extracts from Psidium leaves and fruits. Food Res Int. 2021;141:110070. doi:10.1016/j.foodres.2020.110070
- Oh TW, Do HJ, Jeon JH, Kim K. Quercitrin inhibits platelet activation in arterial thrombosis. Phytomedicine. 2021;80:153363. doi:10.1016/j.phymed.2020.153363
